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NANOLIVE Publications

Nanolive Scientific Publications

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2022

Preparation of a camptothecin analog FLQY2 self‑micelle solid dispersion with improved solubility and bioavailability
Authors: Yi Wang; Wenchao Wang; Endian Yu; Wenya Zhuang; Xuanrong Sun; Hong Wang; Qingyong Li

https://doi.org/10.1186/s12951-022-01596-2, 2022

Published in: Journal of Nanobiotechnology

Tags: Camptothecin, Soluplus®, Solid dispersion, Micelle, Solubility, Pharmacokinetics, In vivo antitumor activity

 

 

Changes of cell membrane fluidity for mesenchymal stem cell spheroids on biomaterial surfaces

Authors: Chui-Wei Wong; Hao-Wei Han; Shan-hui Hsu

https://dx.doi.org/10.4252/wjsc.v14.i8.616, 2022

Published in: World Journal of Stem Cells

Tags: Cell membrane fluidity; Cell-cell interaction; Cellular spheroids; Chitosan; Hyaluronan

 

Early Pharmacological Profiling of Antiproliferative Compounds by Live Cell Imaging

Authors: Adrián Puerta; Aday González-Bakker; Guido Santos; José M. Padrón

https://doi.org/10.3390/molecules27165261, 2022

Published in: Molecules

Tags: phenotypic drug discovery; cancer; natural products; live cell imaging; machine learning; antimitotic drugs; microtubule binding drugs

 

Regulatory Programs of B-cell Activation and Germinal Center Reaction Allow B-ALL Escape from CD19 CAR T-cell Therapy

Authors: Nam Gyu Im; Amy Guillaumet-Adkins; Megha Wal; Anna J. Rogers; Julia Frede; Claire C. Havig; Jing Yang; Praveen Anand; Sarah K. Stegmann; Johannes M. Waldschmidt; Noori Sotudeh; Leili Niu; Jordan Voisine; Michal R. Schweiger; Clemens Grassberger; Jens G. Lohr; Birgit Knoechel

https://doi.org/10.1158/2326-6066.CIR-21-0626, 2022

Published in: Cancer Immunology Research

Tags: CD19; CAR-T; B-cell acute lymphoblastic leukemia; transcriptional plasticity

 

 

Breast radiotherapy with kilovoltage photons and gold nanoparticles as radiosensitizer: An in vitro study

Authors: Alessia Tudda; Elisabetta Donzelli; Gabriella Nicolini; Sara Semperboni; Mario Bossi; Guido Cavaletti; Roberta Castriconi; Paola Mangili; Antonella del Vecchio; Antonio Sarno; Giovanni Mettivier; Paolo Russo

https://doi.org/10.1002/mp.15348, 2021

Published in: Medical Physics

Tags: breast cancer, breast radiotherapy, gold nanoparticles, kilovoltage radiotherapy

 

 

Polymer chimera of stapled oncolytic peptide coupled with anti-PD-L1 peptide boosts immunotherapy of colorectal cancer

Authors: Lu Lu; He Zhang; Yudong Zhou; Jiayi Lin; Weidong Gao; Ting Yang; Jinmei Jin; Lijun Zhang; Dale G. Nagle; Weidong Zhang; Ye Wu; Hongzhuan Chen; Xin Luan

https://doi.org/10.7150/thno.71129, 2022

Published in: Theranostics

Tags: colorectal cancer, stapled mastoparan peptide, peptide-polymer conjugate, immunogenic cell death, oncolytic immunotherapy

 

 

A murine periodontitis model using coaggregation between human pathogens and a predominant mouse oral commensal bacterium

Authors: Mengmeng Liu; Youngnim Choi

https://doi.org/10.5051/jpis.2104360218, 2021

Published in: Journal of Periodontal & Implant Science

Tags: Animal models; Mice; Periodontitis; Porphyromonas gingivalis; Streptococcus danieliae

 
 

Δ9-Tetrahydrocannabinol (Δ9-THC) Improves Ischemia/Reperfusion Heart Dysfunction and Might Serve as a Cardioprotective Agent in the Future Treatment

Authors: Marta Banaszkiewicz; Paulina Tarwacka; Anna Krzywonos-Zawadzka; Agnieszka Olejnik; Robert Laprairie; Agnieszka Noszczyk-Nowak; Grzegorz Sawicki; Iwona Bil-Lula

https://doi.org/10.31083/j.fbl2704114, 2022

Published in: Frontiers in Bioscience-Landmark

Tags: 5-hydroxytryptamine (5-HT), serotonergic, axon, growth cone, varicosities, development, in vitro, random walk

 


High-Resolution Spatiotemporal Analysis of Single Serotonergic Axons in an In Vitro System

Authors: Melissa Hingorani; Adele M.L. Viviani; Jenna E. Sanfilippo; Skirmantas Janušonis

https://doi.org/10.1101/2022.07.16.500161, 2022

Published in: bioRxiv

Tags: 5-hydroxytryptamine (5-HT), serotonergic, axon, growth cone, varicosities, development, in vitro, random walk

 

 

Low-Temperature Synthesis of Hollow β-Tricalcium Phosphate Particles for Bone Tissue Engineering Applications

Authors: Iman Roohani; Young Jung No; Betty Zuo; Sue D. Xiang; Zufu Lu; Hongwei Liu; Magdalena Plebanski; Hala Zreiqat

https://doi.org/10.1021/acsbiomaterials.1c01018, 2022

Published in: ACS Biomaterials Science & Engineering

Tags: β-tricalcium phosphate, bone tissue engineering, bioceramic, synthesis

 

 

The Enhancement of Antimicrobial Photodynamic Therapy of Escherichia Coli by a Functionalized Combination of Photosensitizers: In Vitro Examination of Single Cells by Quantitative Phase Imaging

Authors: Aleksandra Pietrowska; Iwona Hołowacz; Agnieszka Ulatowska-Jarża; Mateusz Guźniczak; Anna K Matczuk; Alina Wieliczko; Mirela Wolf-Baca; Igor Buzalewicz

https://doi.org/10.3390/ijms23116137, 2022

Published in: International Journal of Molecular Sciences

Tags: antimicrobial photodynamic therapy; photodynamic inactivation; digital holotomography; quantitative phase imaging; Chlorin e6; Pheophorbide a; E. coli

 

 

Cytotoxic and pro-inflammatory effects of molybdenum and tungsten disulphide on human bronchial cells

Authors: Lidia Zapór; Luiza Chojnacka-Puchta; Dorota Sawicka; Katarzyna Miranowicz-Dzierżawska; Jolanta Skowroń

https://doi.org/10.1515/ntrev-2022-0073, 2022

Published in: Nanotechnology Reviews

Tags: molybdenum disulphide; tungsten disulphide; cytotoxicity assay; lung cells; holotomographic microscopy

 

 

A non-canonical vitamin K cycle is a potent ferroptosis suppressor

Authors: Eikan Mishima; Junya Ito; Zijun Wu; Toshitaka Nakamura; Adam Wahida; Sebastian Doll; Wulf Tonnus; Palina Nepachalovich; Elke Eggenhofer; Maceler Aldrovandi; Bernhard Henkelmann; Ken-ichi Yamada; Jonas

https://doi.org/10.1038/s41586-022-05022-3, 2022

Published in: Nature

Tags: Ferroptosis; cell death; vitamin K; naphthoquinones; FSP1-dependent non-canonical; lipid peroxidation

 

 

Cathodoluminescence imaging of cellular structures labeled with luminescent iridium or rhenium complexes at cryogenic temperatures

Authors: Marie Vancová; Radim Skoupý; Eva Ďurinová; Tomáš Bílý; Jana Nebesářová; Vladislav Krzyžánek; Aleš Kolouch; Petr Horodyský

https://doi.org/10.1038/s41598-022-17723-w, 2022

Published in: Scientfic Reports

Tags: cathodoluminescence; iridium; rhenium

 

 

ATP synthase is essential for high conductance but not low conductance Mitochondrial Permeability Transition

Authors: M.A. Neginskaya; S.E. Morris; E.V. Pavlov

https://doi.org/10.1101/2021.11.16.468842, 2022

Published in: bioRxiv

Tags: mitochondria; ATP synthase; MTP

 

 

Mitochondrial dysfunction and epithelial to mesenchymal transition in head neck cancer cell lines

Authors: Maria do Carmo Greier; Annette Runge; Jozsef Dudas; Viktoria Pider; Ira-Ida Skvortsova; Dragana Savic; Herbert Riechelmann

https://doi.org/10.1038/s41598-022-16829-5, 2022

Published in: Scientific Reports

Tags: mitochondria; mesenchymal stem cells; head neck cancer

 

 

A cold-water polysaccharide-protein complex from Grifola frondosa exhibited antiproliferative activity via mitochondrial apoptotic and Fas/FasL pathways in HepG2 cells

Authors: Jiahui Zhao; Kaiyue Liang; Hao Zhong; Shizhu Liu; Peilong Sun; Rongjun He

https://doi.org/10.1016/j.ijbiomac.2022.07.098, 2022

Published in: International Journal of Biological Macromolecules

Tags: G. frondosa; Polysaccharide-protein complex; Cold-water extraction; Structural analysis; HepG2 cell inhibitory activity

 

 

Laminin Receptor-Mediated Nanoparticle Uptake by Tumor Cells: Interplay of Epigallocatechin Gallate and Magnetic Force at Nano–Bio Interface

Authors: Sheng-Chieh Hsu; Nian-Ping Wu; Yi-Ching Lu; Yunn-Hwa Ma

https://doi.org/10.3390/pharmaceutics14081523, 2022

Published in: Pharmaceutics

Tags: magnetic nanoparticles; endocytosis; epigallocatechin gallate; 67LR; Akt

 

 

Comparative analysis of Radachlorin accumulation, localization, and photobleaching in three cell lines by means of holographic and fluorescence microscopy

Authors: A.A. Zhikhoreva, A.V. Belashov, T.N. Belyaeva, A.V. Salova, I.K. Litvinov, E.S. Kornilova, I.V. Semenova, O.S. Vasyutinskii

https://doi.org/10.1016/j.pdpdt.2022.102973, 2022

Published in: Photodiagnosis and Photodynamic Therapy

Tags: photodynamic treatment, malignant cells, fluorescent analysis, digital holographic microscopy, phase images

 

 

Effects of iron modulation on mesenchymal stem cell-induced drug resistance in estrogen receptor-positive breast cancer

Authors: Johanna M. Buschhaus, Shrila Rajendran, Brock A. Humphries, Alyssa C. Cutter, Ayşe J. Muñiz, Nicholas G. Ciavattone, Alexander M. Buschhaus, Tatiana Cañeque, Zeribe C. Nwosu, Debashis Sahoo, Avinash S. Bevoor, Yatrik M. Shah, Costas A. Lyssiotis, Pradipta Ghosh, Max S. Wicha, Raphaël Rodriguez, Gary D. Luker

https://doi.org/10.1038/s41388-022-02385-9, 2022

Published in: Oncogene

Tags: breast cancer, stem cells, iron, lysosome, drug resistance, estrogen-targeted therapy

 

 

Engineering CpG-ASO-Pt-loaded macrophages (CAP@M) for synergistic chemo-/gene-/immuno-therapy

Authors: Yuqi Wang, Lingpu Zhang, Yan Liu, Linlin Tang, Juan He, Xiaqing Sun, Muhsin H. Younis, Daxiang Cui, Haihua Xiao, Dong Gao, Xiang-Yang Kong, Weibo Cai, Jie Song

https://doi.org/10.1002/adhm.202201178, 2022

Published in: Advanced Healthcare Materials

Tags: macrophages; antitumor; drug delivery; immunology; immunotherapy; nanomedicine

 

 

Occurrence of lymphangiogenesis in peripheral nerve autografts contrasts Schwann cell-induced apoptosis of lymphatic endothelial cells in vitro

Authors: Carina Hromada, Jaana Hartmann, Johannes Oesterreicher, Anton Stoiber, Anna Daerr, Barbara Schädl, Eleni Priglinger, Andreas H. Teuschl-Woller, Wolfgang Holnthoner, Johannes Heinzel, David Hercher

https://doi.org/10.3390/biom12060820, 2022

Published in: Biomolecules

Tags: peripheral nerve regeneration, lymphangiogenesis, Schwann cells, lymphatic endothelial cells

 

Modulation of mitochondrial electron transport chain by pyroptosis nanoagonists for photoresponsive tumor destruction

Authors: Penghao Ji, Shenyan Zhang, Peilei Liu, Xi Li, Weichao Bao, Xiangzhi Cui, Minfeng Huo, Jianlin Shi

https://doi.org/10.1016/j.nantod.2022.101511, 2022

Published in: Nanotoday

Tags: Pyroptosis; Oligomycin A; Mitochondrial damage; Oxidative stress; Mild hyperthermia

 

 

Legumain/pH dual-responsive lytic peptide–paclitaxel conjugate for synergistic cancer therapy

Authors: Shanshan Zheng, Yue Cai, Yulu Hong, Yubei Gong, Licheng Gao, Qingyong Li, Le Li, Xuanrong Sun

https://doi.org/10.1080/10717544.2022.2081380, 2022

Published in: Drug Delivery

Tags: Peptide–drug conjugate; legumain-responsive; pH-responsive; synergistic cancer therapy

 

 

Interleukin-13 and its receptor are synaptic proteins involved in plasticity and neuroprotection

Authors: Shun Li, Florian olde Heuvel, Rida Rehman, Zhenghui Li, Oumayma Aousji, Albrecht Froehlich, Wanhong Zhang, Alison Conquest, Sarah Woelfle, Michael Schoen, Caitlin O´Meara, Richard Lee Reinhardt, David Voehringer, Jan Kassubek, Albert Ludolph, Markus Huber-Lang, Bernd Knöll, Maria Cristina Morganti-Kossmann, Tobias Boeckers, Francesco Roselli 

https://doi.org/10.1101/2021.12.01.470746, 2021

Published in: bioRxiv

Tags: IL-13, synapses, CREB, excitotoxicity, traumatic brain injury

 

 

ATP purinergic receptor P2X1-dependent suicidal NETosis induced by Cryptosporidium parvum under physioxia conditions
Authors: Seyed Sajjad Hasheminasab; Iván Conejeros; Zahady D. Velásquez; Tilman Borggrefe; Ulrich Gärtner; Faustin Kamena; Anja Taubert; Carlos Hermosilla

https://doi.org/10.3390/biology11030442, March 2022

Published in: Biology

Tags: Cryptosporidium parvum; NETosis; purinergic receptor P2X1; Notch; glycolysis; PMN

 


N-Acetyl-Cysteine Increases Activity of Peanut-Shaped Gold Nanoparticles Against Biofilms Formed by Clinical Strains of Pseudomonas aeruginosa Isolated from Sputum of Cystic Fibrosis Patients

Authors: Ewelina Piktel; Urszula Wnorowska; Joanna Depciuch; Dawid Łysik; Mateusz Cieśluk; Krzysztof Fiedoruk; Joanna Mystkowska; Magdalena Parlińska-Wojtan; Paul A Janmey; Robert Bucki

https://doi.org/10.2147/IDR.S348357, 2022

Published in: Infection and Drug Resistance

Tags: gold nanoparticles, non-spherical nanoparticles, N-acetyl-cysteine, bacteria biofilm, cystic fibrosis, Pseudomonas aeruginosa

St. Thomas Modified Cardioplegia Effects on Myoblasts’ Viability and Morphology
Authors: Rafał Nowicki; Katarzyna Biezuska-Kusiak; Julita Kulbacka; Anna Choromanska; Małgorzata Daczewska; Stanisław Potoczek; Maciej Rachwalik; Jolanta Saczko

https://doi.org/10.3390/medicina58020280, 2022

Published in: Medicina

Tags: rat heart myocardium cells; proliferating antigens; thiol groups; cold crystalloid cardioplegia

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Novel insights into sterol uptake and intracellular cholesterol trafficking during Eimeria bovis macromeront formation

Authors: Liliana M. R. Silva; Zahady D. Velasquez; Sara Lopez-Osorio; Carlos Hermosilla; Anja Taubert

https://doi.org/10.3389/fcimb.2022.809606, 2022

Published in: Frontiers in Cellular and Infection Microbiology

Tags: LDL sources; cholesterol trafficking; parasite acquisition of nutrients; ezetimibe; progesterone; U18666A

Identification of shared tumor epitopes from endogenous retroviruses inducing high-avidity cytotoxic T cells for cancer immunotherapy

Authors: Paola Bonaventura; Vincent Alcazer; Virginie Mutez; Laurie Tonon; Juliette Martin; Nicolas Chuvin; Emilie Michel; Rasha E. Boulos; Yann Estornes; Jenny Valladeau-Guilemond; Alain Viari; Qing Wang; Christophe Caux; Stéphane Depil

https://doi.org/10.1126/sciadv.abj3671, 2022

Published in: Science Advances

Tags: adaptive immunity; Human endogenous retroviruses; cancer vaccine; immunotherapy; solid tumors

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Treponema denticola Promotes OSCC Development via the TGF-β Signaling Pathway

Authors: R.T. Peng, Y. Sun, X.D. Zhou, S.Y. Liu, Q. Han, L. Cheng, X. Peng

https://doi.org/10.1177/00220345211067401, 2022

Published in: Journal of Dental Research

Tags: bacteria, Spirochaetaceae, carcinoma, cell growth processes, cell proliferation, transforming growth factors

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2021

New Data on Variously Directed Dose-Response Relationships and the Combined Action Types for Different Outcomes of in Vitro Nanoparticle Cytotoxicity

Authors: Vladimir Panov; Tatiana Bushueva; Ilzira Minigalieva; Anna Naumova; Vladimir Shur; Ekaterina Shishkina; Marina Sutunkova; Vladimir Gurvish; Larisa Privalova; Boris Katsnelson

https://doi.org/10.1177/15593258211052420, 2021

Published in: Dose-Response

Tags: nanoparticles; selenium-oxide; copper-oxide; dose-response relationships; hormesis


The Cellular Innate Immune Response of the Invasive Pest Insect Drosophila suzukii against Pseudomonas entomophila Involves the Release of Extracellular Traps

Authors: Tessa Carrau; Susanne Thümecke; Liliana M. R. Silva; David Perez-Bravo; Ulrich Gärtner; Anja Taubert; Carlos Hermosilla; Andreas Vilcinskas; Kwang-Zin Lee

https://doi.org/10.3390/cells10123320, 2021

Published in: Cells

Tags: cell culture; Drosophila suzukii; hemocytes; plasmatocytes; extracellular traps

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Thiosemicarbazone Copper Chelator BLT-1 Blocks Apicomplexan Parasite Replication by Selective Inhibition of Scavenger Receptor B Type 1 (SR-BI)

Authors: Camilo Larrazabal; Sara López-Osorio; Zahady D. Velásquez; Carlos Hermosilla; Anja Taubert; Liliana M. R. Silva

https://doi.org/10.3390/microorganisms9112372, 2021

Published in: Microorganisms

Tags: Toxoplasma gondii; Neospora caninum; Besnoitia besnoiti; Eimeria bovis; Eimeria arloingi; SR-BI; HDL; BLT-1

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Morphometric analysis of aerobic Eimeria bovis sporogony using live cell 3D holotomographic microscopy imaging

Authors: Sara Lopez‑Osorio; Zahady D. Velasquez; Iván Conejeros; Anja Taubert; Carlos Hermosilla

https://doi.org/10.1007/s00436-021-07338-x, 2021

Published in: Parasitology Research

Tags: Eimeria bovis; Oocyst; Sporogony; 3D holotomographic microscopy; Live cell imaging

 

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Mitochondrial Dynamics in SARS‑COV2 Spike Protein Treated Human Microglia: Implications for Neuro‑COVID

Authors: Erin Clough; Khoo Ting Chean; Joseph Inigo; Kate E. Tubbesing; Dhyan Chandra; Lee Chaves; Jessica L. Reynolds; Ravikumar Aalinkeel; Stanley A. Schwartz; Alexander Khmaladze; Supriya D. Mahajan

https://doi.org/10.1007/s11481-021-10015-6, 2021

Published in: Journal of Neuroimmune Pharmacology

Tags: SARS-COV2; Microglia; Neuro-inflammation; Oxidative stress; Mitochondrial dysfunction; Neuro-COVID

 

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AlPc/ZnPc-based oncological photodynamic therapy for a selective eradication of leukemic cells from ovarian tissue

Authors: Saeid Moghassemi; Arezoo Dadashzadeh; Paulo Eduardo Narcizode Souza; Ricardo Bentes Azevedo; Christiani A. Amorim

https://doi.org/10.1016/j.pdpdt.2021.102555, 2021

Published in: Photodiagnosis and Photodynamic Therapy

Tags: Photodynamic therapy; cancer therapy; photosensitizer; ovarian transplantation; leukemia; phthalocyanine; photoimmunotherapy

 

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P2RY12-Inhibitors Reduce Cancer-Associated Thrombosis and Tumor Growth in Pancreatic Cancers

Authors: Ana Luisa Palacios-Acedo; Soraya Mezouar; Diane Mège; Lydie Crescence; Christophe Dubois; Laurence Panicot-Dubois

https://doi.org/10.3389/fonc.2021.704945, 2021

Published in: Frontiers in Oncology

Tags: pancreatic tumors; thrombosis; clopidogrel; aspirin; P2Y12 receptor

 

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Artificial Intelligence-Powered Automated Holotomographic Microscopy Enables Label-Free Quantitative Biology

Authors: Hugo Moreno, Lorenzo Archetti, Emma Gibbin, Alexandre E. Grandchamp, and Mathieu Fréchin

https://doi.org/10.1017/S1551929521001139, 2021

Published in: Microscopy Today

Tags: microscopy; drug research; cell biology; computer vision; artificial intelligence

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Carbon-based nanomaterials increase reactivity of primary monocytes towards various bacteria and modulate their differentiation into macrophages

Authors: Tereza Svadlakova; Martina Kolackova; Radka Vankova; Rumeysa Karakale; Andrea Malkova; Pavel Kulich; Frantisek Hubatka; Pavlina Turanek-Knotigova; Irena Kratochvilova; Milan Raska; Jan Krejsek; Jaroslav

https://doi.org/10.3390/nano11102510, 2021

Published in: Nanomaterials

Tags: graphene; carbon nanotubes; cytotoxicity; immunomodulation; inflammation; monocytes; phagocytosis

 

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Berberine photo‐activation potentiates cytotoxicity in human astrocytoma cells through apoptosis induction

Authors: Francesca Carriero; Carolina Martinelli; Fabio Gabriele; Giulia Barbieri; Lisa Zanoletti; Gloria Milanesi; Claudio Casali; Alberto Azzalin; Federico Manai; Mayra Paolillo; Sergio Comincini

https://doi.org/10.3390/jpm11100942, 2021

Published in: Journal of Personalized Medicine

Tags: oxidative stress; phyto-therapy; astrocytoma; glial tumor

 

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Label-free quantitative phase imaging reveals spatial heterogeneity of extracellular vesicles in selected colon disorders

Authors: Łukasz Zadka; Igor Buzalewicz; Agnieszka Ulatowska-Jarża; Agnieszka Rusak; Maria Kochel; Ireneusz Ceremuga; Piotr Dzięgiel

https://doi.org/10.1016/j.ajpath.2021.08.005, 2021

Published in: The American Journal of Pathology

Tags: digital holographic tomography; extracellular vesicles; Evs; colorectal cancer; ulcerative colitis

 

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Confined migration promotes cancer metastasis through resistance to anoikis and increased invasiveness

Authors: Deborah Fanfone; Zhi Chong Wu; Jade Mammi; Kevin Berthenet; David Neves; Kathrin Weber; Andrea Halaburkova; François Virard; Félix Bunel; Hector Hernandez-Vargas; Stephen WG Tait; Anca Hennino; Gabriel Ichim

https://doi.org/10.1101/2021.08.17.456592, 2021

Published in: bioRxiv

Tags: metastasis; invasion; anoikis; cancer; motility; evasion; resistance

 

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Controlled release of hydrogen by implantation of magnesium induces P53-mediated tumor cells apoptosis

Authors: Rui Zan; Hao Wang; Weijie Cai; Jiahua Ni; Bérengère J. C. Luthringer-Feyerabend; Wenhui Wang; Hongzhou Peng; Weiping Ji; Jun Yan; Jiazeng Xia; Yang Song; Xiaonong Zhang

https://doi.org/10.1016/j.bioactmat.2021.07.026, 2021

Published in: Bioactive Materials

Tags: Biodegradable magnesium; hydrogen; tumor apoptosis; underlying mechanism; P53

 

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Eimeria bovis macromeront formation induces glycolytic responses and mitochondrial changes in primary host endothelial cells

Authors: Zahady D. Velásquez; Sara López-Osorio; Sybille Mazurek; Carlos Hermosilla; Anja Taubert

https://doi.org/10.3389/fcimb.2021.703413, 2021

Published in: Frontiers in Cellular and Infection Microbiology

Tags: apicomplexan parasites; Eimeria bovis; endothelial cell; senescence; mitochondrial damage; reactive oxygen products

 

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Non-thermal atmospheric pressure plasma-conditioned root dentin promotes attraction and attachment of primary human dental pulp stem cells in real-time ex vivo

Authors: Yeon-Jee Yoo; Min-Ji Kang; Hiran Perinpanayagam; Joo-Cheol Park; Seung-Ho Baek; Kee-Yeon Kum

https://doi.org/10.3390/app11156836, 2021

Published in: Applied Sciences

Tags: dentin; human dental pulp stem cells; live-cell imaging; MTT assay; non-thermal atmospheric pressure plasma; scanning electron microscopy

 

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Intracellular detection and localization of nanoparticles by refractive index measurement

Authors: Alain Géloën; Karyna Isaieva; Mykola Isaiev; Olga Levinson; Emmanuelle Berger; Vladimir Lysenko

https://doi.org/10.3390/s21155001, 2021

Published in: Sensors

Tags: label-free imaging; refractive index; nanoparticle; quantitative image analysis; real-time analysis; single cell analysis; digital holographic microscope

 

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Environmental free-living amoebae can predate on diverse antibiotic-resistant human pathogens

Authors: Félix Bornier; Eline Zas; Damien Potheret; Maria-Halima Laaberki; Bénédicte Coupat-Goutaland; Xavier Charpentier

https://doi.org/10.1128/AEM.00747-21, 2021

Published in: Applied and Environmental Microbiology

Tags: antibiotic resistance; amoebae; phagocytes; bactericidal

 

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Mitochondrial Transplantation in Cardiomyocytes: foundation, methods, and outcomes

Authors: Paria Ali Pour; Sina Hosseinian; Arash Kheradvar

https://doi.org/10.1152/ajpcell.00152.2021, 2021

Published in: American Journal of Physiology: Cell Physiology

Tags: mitochondrial transplantation; mitochondrial transfer, mitochondrial diseases, mitochondrial cardiomyopathy, ischemia reperfusion injury, bioenergetics

 

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2020

BA6 Induces Apoptosis via Stimulation of Reactive Oxygen Species and Inhibition of Oxidative Phosphorylation in Human Lung Cancer Cells

Authors: Lianna Y. D’Brant, Habben Desta, Ting Chean Khoo, Anna V. Sharikova, Supriya D. Mahajan, Alexander Khmaladze.

Published in Journal of Biomedical Optics

Published: 29 February 2020

 

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Neutrophils are mediators of metastatic prostate cancer progression in bone

Authors: Costanzo-Garvey, D.L., Keeley, T., Case, A.J. et al.

Published in Cancer Immunology, Immunotherapy

Published: 29 February 2020

 

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Neutrophils are mediators of metastatic prostate cancer progression in bone

Authors: Costanzo-Garvey, D.L., Keeley, T., Case, A.J. et al.

Published in Cancer Immunology, Immunotherapy

Published: 29 February 2020

 

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Neutrophils are mediators of metastatic prostate cancer progression in bone

Authors: Costanzo-Garvey, D.L., Keeley, T., Case, A.J. et al.

Published in Cancer Immunology, Immunotherapy

Published: 29 February 2020

 

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Stimuli-sensitive fatty acid-based microparticles for the treatment of lung cancer

Authors: Katarzyna Reczyńska, Patrycja Marchwica, Dipesh Khanal, Tomasz Borowik, Marek Langner, Elżbieta Pamuła, Wojciech Chrzanowski

Published in Materials and Science Engineering: C

Published: 2020, Volume 111, June 2020, 110801 

 

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Neutrophils are mediators of metastatic prostate cancer progression in bone

Authors: Costanzo-Garvey, D.L., Keeley, T., Case, A.J. et al.

Published in Cancer Immunology, Immunotherapy

Published: 29 February 2020

 

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Proinflammatory Effect of Carbon-Based Nanomaterials: In Vitro Study on Stimulation of Inflammasome NLRP3 via Destabilisation of Lysosomes

Authors: Svadlakova, T.; Hubatka, F.; Turanek Knotigova, P.; Kulich, P.; Masek, J.; Kotoucek, J.; Macak, J.; Motola, M.; Kalbac, M.; Kolackova, M.; Vankova, R.; Vicherkova, P.; Malkova, A.; Simeckova, P.; Volkov, Y.; Prina-Mello, A.; Kratochvilova, I.; Fiala, Z.; Raska, M.; Krejsek, J.; Turanek, J

Published in Nanomaterials

Nanomaterials 202010(3), 418

 
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Molecular heterogeneity in breast carcinoma cells with increased invasive capacities

Authors: Giulia Negro, Bertram Aschenbrenner, Simona Kranjc Brezar, Maja Cemazar, Andrej Coer, Gorana Gasljevic, Dragana Savic, Maxim Sorokin, Anton Buzdin, Maurizio Callari, Irma Kvitsaridze, Anahid Jewett, Mariela Vasileva-Slaveva, Ute Ganswindt, Prof. Ira Skvortsova, Sergej Skvortsov

Published in The Journal of Association of Radiology and Oncology

14 February 2020

 
 

Enhancement of the biological autoluminescence by mito-liposomal gold nanoparticle nanocarriers

Authors: Hadi Sardarabadi, Djamel Eddine Chafai, Fatemeh Gheybi, Pezhman Sasanpour, Hashem Rafii-Tabar, Michal Cifra

Published in Journal of Photochemistry and Photobiology B: Biology

Volume 204, March 2020, 111812

 

Optimized excystation protocol for ruminant Eimeria bovis- and Eimeria arloingi-sporulated oocysts and first 3D holotomographic microscopy analysis of differing sporozoite egress

Authors: Sara López-Osorio, Liliana M.R.Silva, Jenny J.Chaparro-Gutierréz, Zahady D.Velazquez, Anja Taubert, Carlos Hermosilla

Published in Parasitology International

Parasitology International: Volume 76, 2020, 102068

 

PGRMC1 phosphorylation affects cell shape, motility, glycolysis, mitochondrial form and function, and tumor growth

Authors: Bashar M. Thejer, Partho P. Adhikary, Amandeep Kaur et al.

Published in BMC Molecular and Cell Biology

Published: January2020

 

Impaired Glycolysis Promotes Alcohol Exposure-Induced Apoptosis in HEI-OC1 Cells via Inhibition of EGFR Signaling

Authors: Hyunsook Kang, Seong Jun Choi, Kye Hoon Park, Chi-Kyou Lee, and Jong-Seok Moon

Published in International Journal of Molecular Sciences

Int. J. Mol. Sci. 202021(2), 476

 

A Gain-Of-Function RAC2 Mutation Is Associated With Bone-Marrow Hypoplasia And An Autosomal Dominant Form Of Severe Combined Immunodeficiency

Authors: Chantal Lagresle-PeyrouAurélien OlichonHanem SadekPhilippe RocheClaudine TardyCindy Da SilvaAlexandrine GarrigueAlain FischerDespina MoshousYves ColletteCapucine PicardJean Laurent CasanovaIsabelle AndréMarina Cavazzana

Published in Haematologica Journal of The Ferrata Storti Foundation

 

Caspase-8 deficiency induces a switch from TLR3-induced apoptosis to lysosomal cell death in neuroblastoma cell lines

Authors: Marie-Anaïs LocquetGabriel IchimAurelie DutourSerge LebequeMarie CastetsKathrin Weber

Published in BioRxiv

Published: January 14, 2020

 

A potential hydrodynamic mechanism for cytoplasmic transfer between mammalian cells: Cell-projection pumping

Authors: Hans Zoellner, Navid Paknejad, James Cornwell, Belal Chami, Yevgeniy Romin, Vitaly Boyko, Sho Fujisawa, Elizabeth Kelly, Garry W. LynchGlynn RogersKatia ManovaMalcolm A.S. Moore

Published in BioRxiv

Published: January, 2020

 

2019

 

Besnoitia besnoiti bradyzoite stages induce suicidal- and rapid vital-NETosis

Authors: Ershun ZhouLiliana M. R. SilvaIván ConejerosZahady D. VelásquezManuela HirzUlrich GärtnerPhilippe JacquietAnja Taubert and Carlos Hermosilla

Published in Parasitology

16 December 2019

 

Image-based analysis of living mammalian cells using label-free 3D refractive index maps reveals new organelle dynamics and dry mass flux

Authors: Patrick A. Sandoz, Christopher Tremblay, F. Gisou van der Goot, Mathieu Frechin

PLoS Biol. 2019 Dec; 17(12): e3000553

Published in PLOS Biology

 

E-Cigarette Use Increases Susceptibility to Bacterial Infection by Impairment of Human Neutrophil Chemotaxis, Phagocytosis and NET Formation

Authors: Authors: Ross Corriden, Alexander Moshensky, Christine M Bojanowski, Angela Meier, Jason Chien, Ryan K Nelson, Laura E. Crotty Alexander

Published inAmerican Journal of Physiology

 

S-Nitrosothiol Plasma-Modified Surfaces for the Prevention of Bacterial Biofilm Formation

Authors: Zahra Sadrearhami, Rashin Namivandi-Zangeneh, Emily Price, Marta Krasowska, Sameer A Al-Bataineh, Jason Whittle, Edgar H. H. Wong, Anton Blencowe, Cyrille Boyer

Published in ACS Publications

 


Toxoplasma gondii-induced host cellular cell cycle dysregulation is linked to chromosome missegregation and cytokinesis failure in primary endothelial host cells

Authors: Velásquez ZD, Conejeros , Larrazabal C , Kerner K, Hermosilla C, Taubert A

Published in PubMed

 


Beyond the suprachiasmatic nucleus: circadian rhythmicity shapes astrocyte morphology and neuronal function in hippocampal area CA1

Authors: John P. McCauley, Maurice A. Petroccione, Lianna Y. D’Brant, Gabrielle C. Todd, Nurat Affinnih, Justin J. Wisnoski, Shergil Zahid, Swasti Shree, Alioscka A. Sousa, Rosanna Migliore, Alexey Brazhe, Richard D. Leapman, Alexander Khmaladze, Alexey Semyanov, Michele Migliore and Annalisa Scimemi

Published in bioRxiv

 

Autophagosome accumulation-mediated ATP energy deprivation induced by penfluridol triggers nonapoptotic cell death of lung cancer via activating unfolded protein response

Authors: Wen-Yueh Hung, Jer-Hwa Chang, Yu Cheng, Guo-Zhou Cheng, Hsiang-Ching Huang, Michael Hsiao, Chi-Li Chung, Wei-Jiunn Lee and Ming-Hsien Chien

Published in Springer Nature

 

Quantification of changes in cellular morphology during cell necrosis obtained from 3D refractive index distributions

Authors: D A GorbenkoA V BelashovT N BelyaevaE S KornilovaI V Semenova and O S Vasyutinskii

Published in Journal of Physics

 

Pleiotropic Effects of Epithelial Mesenchymal Crosstalk on Head and Neck Cancer: EMT and beyond

Authors: T. B. Steinbichler, D. Savic, D. Dejaco, A. Romani, B. Kofler, I. I. Skvortsova, H. Riechelmann, J. Dudas

Published in Cancer Microenvironment

Endocytosis-mediated mitochondrial transplantation: Transferring normal human astrocytic mitochondria into glioma cells rescues aerobic respiration and enhances radiosensitivity

Authors: Chao Sun, Xiongxiong Liu, Bing Wang, Zhenhua Wang, Yang Liu, Cuixia Di, Jing Si, Hongyan Li, Qingfeng Wu, Dan Xu, Ji Li, Gang Li, Yupei Wang, Fang Wang and
Hong Zhang

Published in Theranostics

BA6 Induces Apoptosis via Stimulation of Reactive Oxygen Species and Inhibition of Oxidative Phosphorylation in Human Lung Cancer Cells

Authors: Meng-Hsuan ChengHung-Ling HuangYen-You LinKuan-HaoTsuiPei-Chin ChenShu-Yu ChengInn-Wen ChongPing-JyunSungMing-Hong TaiZhi-Hong WenNan-Fu Chen, and Hsiao-Mei Kuo

Published in Oxidative Medicine and Cellular Longevity journal

Impact of the Food Additive Titanium Dioxide (E171) on Gut Microbiota-Host Interaction

Authors: Gabriela Pinget, Jian Tan, Bartlomiej Janac, Nadeem O. Kaakoush, Alexandra Sophie Angelatos, John O’Sullivan6, Yen Chin Koay, Frederic Sierro, Joel Davis, Shiva Kamini Divakarla, Dipesh Khanal, Robert J. Moore, Dragana Stanley, Wojciech Chrzanowski and Laurence Macia

Published in frontiers in Nutrition

Besnoitia besnoiti infection alters both endogenous cholesterol de novo synthesis and exogenous LDL uptake in host endothelial cells

Authors: Liliana M. R. Silva, Dieter Lütjohann, Penny Hamid, Zahady D. Velasquez, Katharina Kerner, Camilo Larrazabal, Klaus Failing, Carlos Hermosilla & Anja Taubert

Published in nature Scientific Reports

Methamphetamine-induced apoptosis in glial cells examined under markerfree imaging modalities

Authors: Lianna Y. D’Brant, Habben Desta, Ting Chean Khoo, Anna V. Sharikova, Supriya D. Mahajan, Alexander Khmaladze

Published in Journal of Biomedical Optics

Synthesis of fluorescent molybdenum nanoclusters at ambient temperature and their application in biological imaging

Authors: Amit Kumar Sharma, Sunil Pandey, Nallin Sharma, Hui-Fen Wu

Published in Science Direct

Diagnosing water treatment critical control points for cyanobacterial removal: Exploring benefits of combined microscopy, next-generation sequencing, and cell integrity methods

Authors: Arash Zamyadi, Caitlin Romanis, Toby Mills, Brett Neilan, Florence Choo, Lucila A., Coral, Deb Gale, Gayle Newcombe, Nick Crosbie, Richard Stuetz, Rita K. Henderson

Published in Science Direct

Antibiofilm Nitric Oxide Releasing Polydopamine Coatings

Authors: Zahra Sadrearhami, Farah Nabilah Shafiee, Kitty Ka Kit Ho, Naresh Kumar, Marta Krasowska, Anton Blencowe, Edgar H. H. Wong, and Cyrille Boyer

Published in ACS Publications

Degradation of Mitochondria and Oxidative Stress as the Main Mechanism of Toxicity of Pristine Graphene on U87 Glioblastoma Cells and Tumors and HS-5 Cells

Authors: Sławomir Jaworski, Barbara StrojnyEwa Sawosz, Mateusz WierzbickiMarta GrodzikMarta KutwinKarolina Daniluk and André Chwalibog 

Published in Publishing International Journal of Molecular Sciences

Morphological changes in the ovarian carcinoma cells of Wistar rats induced by chemotherapy with cisplatin and dioxadet

Authors: A. A. Zhikhoreva, A. V. Belashov, V. G. Bespalov, A. L. Semenov, I. V. Semenova, G. V. Tochilnikov, N. T. Zhilinskaya, and O. S. Vasyutinskii

Published in OSA Publishing

Label free 3D analysis of organelles in living cells by refractive index shows pre-mitotic organelle spinning in mammalian stem cells

Authors: Patrick A SandozChristopher TremblaySebastien EquisSorin PopLisa PollaroYann CotteGisou F van der GootMathieu Frechin

Pre-published in bioRxiv

Label-Free Digital Holo-tomographic Microscopy Reveals Virus-Induced Cytopathic Effects in Live Cells

Authors: Artur YakimovichRobert WitteVardan AndriasyanFanny GeorgiUrs F Greber

Published in American Society for Microbiology

Parvalbumin alters mitochondrial dynamics and affects cell morphology

Authors: Lucia Lichvarova, Thomas Henzi, Dzhamilja Safiulina, Allen Kaasik, Beat Schwaller

Published in: Springer Link

Superresolved and reference-free microparticle traction force microscopy (MP-TFM) reveals the complexity of the mechanical interaction in phagocytosis

Authors: Daan VorselenYifan WangMatthew J FooterWei CaiJulie A Theriot

Pre-published in bioRxiv

Live-stream characterization of cadmium-induced cell death using visible CdTe-QDs

Authors: Samira Filali, Alain Geloën, Vladimir Lysenko, Fabrice Pirot & Pierre Miossec

Published in: Scientific Reports 

Nanoparticles Based on Poly(trimethylene carbonate) Triblock Copolymers with Post-Crystallization Ability and Their Degradation in vitro

Authors: Lucie Reinišová, Filip Novotný, Martin Pumera, Katarína Kološtová, Soňa Hermanová

Published in: Springer Link 

Enhancing the antimicrobial and antibiofilm effectiveness of silver nanoparticles prepared by green synthesis

Published in: Journal of Materials Chemistry B

Nitric Oxide-Loaded Antimicrobial Polymer for the Synergistic Eradication of Bacterial Biofilm

Authors: Rashin Namivandi-Zangeneh, Zahra Sadrearhami, Ali Bagheri, Maeva Sauvage-Nguyen,
Kitty Ka Kit Ho,Naresh Kumar, Edgar H. H. Wong, and Cyrille Boyer

Published in: ASC Macro Letter

The Effects of Polymer Topology and Chain Length on the Antimicrobial Activity and Hemocompatibility of Amphiphilic Ternary Copolymers

Published in: Polymer Chemistry Journal

Facile preparation of full-color emissive carbon dots and their applications in imaging of the adhesion of erythrocytes to endothelial cells

Published in: Journal of Materials Chemistry B

The selexipag active metabolite ACT-333679 displays strong anti-contractile and anti- remodeling effects, but low β-arrestin recruitment and desensitization potential

Authors: John GatfieldKatalin MenyhartDaniel WannerCarmela GnerreLucile MonnierKeith MorrisonPatrick HessMarc IglarzMartine Clozel and Oliver Nayler.

Published in: The Journal of Pharmacology and Experimental Therapeutics, 2017

Live Single-cell Mass Spectrometry with Spatial Quantitation by Three-Dimensional Holographic and Tomographic Laser Microscopy

Authors: Ali A, Abouleila Y, Amer S, Furushima R, Emara S, Equis S, Cotte Y, Masujima T

Published in: Analytical Sciences as Rapid Communication, 2016