Expertise in scientific imaging

CQ1-Yokogawa

CQ1 Benchtop High-Content Analysis System

 

 

CQ1 enables 3D imaging and quantification of live cell clusters, such as spheroids within a 3D culture vessel, as they are, keeping the cells intact. CQ1 exports feature data in general formats which are readable by various third-party software for advanced data analysis. It is possible to construct fully customized CQ1-based system by integrating with external systems*1, via robot for culture dish handling.

 

CQ1 System Highlights

 

Excitation laser wavelength405 nm, 488 nm, 561 nm, 640 nm
Illumination sourceLaser
Objective lens2x to 60x
(Dry, Phase contrast, Long working distance)
CameraHigh-sensitivity sCMOS camera
AutofocusLaser autofocus, Software autofocus
SoftwareCellPathfinder

 

Overview

 

Enables measurement of spheroids, colonies and tissue sections

CQ1

 

 

 

・No need to remove cells from culture dish, in contrast to traditional flow cytometry

・Nipkow spinning disk confocal technology allows high-speed yet gentle 3D image acquisition

・Rich feature extraction to facilitate sophisticated cellular image analysis

・Wide field of view and tiling capability enable easy imaging of large specimen

Enables analysis of time lapse and live cell

 
  • High precision stage incubator and low phototoxicity of our confocal makes the analysis of time lapce and live cell are possible
  • Max.20fps option for fast time lapce
 

High quality image and the similar operability to traditional flow cytometer

 
  • Feature data and statistical graphs displayed in real-time with image acquisition
  • Usuable high quality image as confocal micorscope image
  • Easy to trace back to the original image from a graph spot, and make repetitive measurements
 

Open platform

 
  • Connectable with external systems via handling robot *1
  • Expandable to integrated system as image acquisition and quantification instrument
  • FCS/CSV/ICE data format readable by third-party data analysis software
  • A variety of cell culture and sample dishes are applicable
 

Compact footprint, light weight bench-top device; no need for darkroom

 

 

 CQ1General fluorescent imagingFlow cytometry
Cell removal/suspension treatmentNot necessaryNot necessaryNecessary
Cell image confirmationPossiblePossibleNot possible
Display feature data and graphs in real-time with imagingPossibleDepends on devicesPossible
3D data measurementPossibleNot possibleNot possible
Time lapsePossibleNot possibleNot possible

*1 Contact to CQ1 partner for more information