TIRFM Systems, Olympus
Olympus TIRFM Systems for ultra sensitive fluorescence microscopy at the cell surface, providing high contrast images with minimal background noise.
TIRFM Systems
cell^tool TIRFM
TIRF microscopy system based on the cell^M and cell^R imaging stations
- Cell surface observation without out-of-focus blur
- Fully integrated into cell^M and ^R imaging stations
- Combination of up to three lasers plus a MT10/20 fluorescence illumination system
- Optimised beam alignment on individual laser ports
cell^tool TIRFM System
cell^tool TIRFM is based on a modular multi-port illuminator for up to three lasers and a MT10 or MT20 widefield flourescence light source. This extension of the cell^M and cell^R imaging stations allows for laser based high resolution cell surface and membrane studies with the possibility of simultaneous widefield observation. The control of the TIRFM illuminator is integrated into the 'Experiment Manager' of cell^M and cell^R software, so in addition to highest quality TIRF observation cell^tool TIRFM offers all the powerful options of the cell* imaging stations. The cell^tool TIRFM is available as a complete turn-key solution or as an add-on for existing cell^M or cell^R imaging systems.
Laser-based and white light TIRFM illumination modules for Olympus IX2 microscopes.
TIRFM
Ultra-sensitive fluorescence microscopy
- Ultra-sensitive fluorescence microscopy with unsurpassed Z-resolution at the cell surface
- Simple adjustment of evanescent field illumination
- Simultaneous widefield illumination
TIRFM - illumination module for IX2 microscopes
This laser based TIRFM (Total Internal Reflection Microscopy) illumination module for Olympus IX2 microscopes facilitates the observation of cellular structures down to single molecule fluorescence at surfaces and interfaces with unsurpassed Z-resolution. Special high numerical aperture TIRF objectives guarantee excellent performance in terms of brightness, contrast and resolution. The TIRFM illuminator allows silmultaneous integration of standard widefield fluorescence illumination.
IX2 - ARCEVA
White-light TIRFM illumination module
- Cell surface imaging with high z-resolution
- Minimal background noise
- Wide choice of excitation wavelength
- Cost efficient lightsources
IX2-ARCEVA - white light illumination module
The IX2-ARCEVA was the world?s first Total Internal Reflection Fluorescence Microscopy (TIRFM) solution with evanescent illumination from an arc lamp source. The slit mechanism developed by Olympus provides white light evanescent wave illumination for high signal to noise fluorescence observations with extraordinary thin optical sectioning at the specimen-coverslip interface. This solution for microscopes of the IX2 range enables a wider choice of excitation colours compared to TIRFM systems based on single wavelength laser light sources which in turn are more sensitive.