Imsol - Image Solutions

The ONIX Perfusion System was developed by CellASIC to overcome the limitations encountered with traditional microfluidics setups. Operations that used to take expert engineers hours of tedious tinkering can now be performed in a few minutes on any benchtop. This system is the equivalent of 8 syringe pumps, a perfusion chamber apparatus, and a CO₂ incubator— at a fraction of the cost and greatly improved quality and ease of use.

A low-profile manifold connects the control system with the microfluidic plates. The manifold is set on top of the wells of the plate, and forms an air tight seal using a vacuum mechanism. The wells are addressed with pneumatic pressure to drive liquids into the microfluidic channels. There is no contact between the flow system and the biological solutions (on the microfluidic plate), preventing contamination and lengthy clean-up. Various manifold layouts are available to address different plate formats and application types.

The Bacterial Microfluidic plate (B2) is optimised for time-lapsed imaging of bacteria cells with solution exchange. The unique Microfluidic cell trapping region holds bacteria cells in a uniform focal plane for time-lapse cell microscopy during perfusion flow. 

The B2 plate has an elastic ceiling that traps the bacteria cells, in an area between 0.9-1.4 microns. The trapping site also prevents the cells from moving in and out of focus, meaning it is suitable for use in long time-lapse videos. The microfluidic network also ensures rapid laminar flow exchange and elimination of cross flows between the exposure channels. 

 For more information and to see the rest of the CellASIC range click here